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Plenary and Symposium Recordings

Using Mobile Technology to Enhance Treatment and Research in Psychosis

Chair
Daphne Holt

Presenters
Justin Baker | Inez Myin-Germeys | Tara Niendam | Neil Thomas

Rapid progress and innovation in the uses of digital technology for the study and treatment of mental illness has occurred over the past decade. These approaches are beginning to be widely adopted based on the expectation that they will overcome a number of long-standing limitations of conventional research and treatment of psychotic illness, including the low temporal resolution and dependence on memory recall of self-report and interview-based measures, and the inability of conventional psychotherapies to address symptoms or situations as they present in real time. In this webinar, the current state of this field as it pertains to improving understanding of the phenomenology and treatment of psychosis will be discussed, with an emphasis on both current progress and the remaining unmet goals.

Sensorimotor Abnormalities in Psychosis: Probing the Interface between the Body and the World

Chair
Daphne Holt

Co-Chair
Francesca Ferri

Presenters
Francesca Ferri | Daphne Holt | Sohee Park | Sebastian Walther

Discussant
Roy Salomon

This panel will present behavioral, neurophysiological and clinical data that evaluate the sensorimotor systems involved in perceiving and acting at the interface between oneself and the outside world, in healthy and psychotic individuals.

Beyond D2 Receptor Blockade: From Mechanisms to New Treatments for Psychosis

Chair
Oliver Howes

Co-Chair
Anissa Abi-Dargham

Presenters
Ragy Girgis | Eric Chen | Oliver Howes | Daniel Lodge

This symposium aims to consider the latest clinical and preclinical evidence on the neurobiology underlying the development of psychosis and resilience against psychosis. It includes clinical, preclinical and translational data and participants from diverse perspectives.

Computational Approaches to Understand Psychosis

Chair
Deanna Barch

Presenters
Tiago Maia | Andreas Meyer-Lindenberg | Kerstin Ritter

This plenary webinar highlights the state-of-the art in computational approaches being used to understand the identification of psychosis, as well as the mechanisms that contribute to its development. The approaches presented will include machine learning, computational modeling, and the use of large-scale electronic medical records.

The Cognitive Journey From Phenotypic Description to Biomarker Identification: A Common Pathway Across Psychosis Spectrum Landscapes

Chair
Lana Kambeitz-Ilankovic

Presenters
Linda Antonucci | Lana Kambeitz-Ilankovic | Mercedes Perez-Rodriguez

This webinar will aim to further understand how cognition may inform the multidimensional nature of psychosis spectrum disorders and provide potent cognitive biomarkers across stringent diagnostic boundaries.

Current State of Treatment of First Episode Psychosis

Chair
Koksal Alptekin

Presenter
Merete Nordentoft 

Mental illness is associated with high burden of disease and it has severe individual and societal consequences. Genetic studies have identified risk genes for schizophrenia, but translation of genetic research into clinical practice is not possible yet. In first episode psychosis, early Intervention services with team-based intensive case management and family involvement are superior to standard treatment in reducing psychotic and negative symptoms and comorbid substance abuse and improving social functioning and user satisfaction. The results of the OPUS-trial will be presented together with meta-analyses based on similar trials.

Advances in the Assessment of Individual Symptom Expression, Dynamics and Course

Discussant
Lindy-Lou Boyette

Presenters
Adela- Maria Isvoranu | Joni L. Mihura

This symposium will present several advances in clinical research on psychotic symptoms, focusing on the transition to the individual level, as well as on symptom dynamics and new measures of thought disorder.

Should we tell Young People They are at Risk for Psychosis? An International Perspective

Chair
Cheryl Corcoran

Co-Chair
Yulia Landa

Presenters
Carmel Loughland | Yulia Landa | Alexandre Loch | Dan Koren

In 2019, the SIRS Ethics Committee Symposium focused on the ethical perspective of psychosis prevention. In the Q and A, there were many questions about labeling of psychosis risk, for which no data had been presented, and for which there was a general assumption among the speakers that such labels are stigmatizing, such that the harm/risks seemed to outweigh the benefits of the risk label. However, data exists that shows that diagnosis and labels related to psychosis and its risk states can have real benefits, providing organizing information to young people and their families, especially if done within the context of thoughtful psychoeducation that includes strategies for accomplishing life goals.

Learning under Uncertainty in Different Stages of Psychosis

Chair
Franziska Knolle

Presenters
Kelly Diederen | Teresa Katthagen | Franziska Knolle

With this symposium, we are bringing together different experimental studies using a variety of methods such as behavioural work, functional imaging, FDOPA-PET and pharmacological intervention to investigate these recent theories experimentally, and to explore whether learning under uncertain, probabilistic circumstances is suboptimal in individuals suffering from psychotic symptoms at different stages of the disease and linked to psychotic symptoms.

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